AI Connector
Overview
CAN-IMMUNE can be queried from Claude, ChatGPT and other AI assistants through a Model Context Protocol (MCP) server. Once connected, you can ask about genes, cell lines, tissues, cancer types, mutations and cached MHC-I binding predictions in plain language. Access is read-only.
https://canelib.erc.monash.edu/mcp Streamable HTTP. No sign-in needed; signing in with Google gives a higher rate limit.
Setup
- Claude (claude.ai): Settings → Connectors → Add custom connector, then paste the URL above.
- Claude Code: claude mcp add --transport http canelib https://canelib.erc.monash.edu/mcp
- ChatGPT (Pro developer mode, Business or Enterprise): Settings → Connectors, then add the URL. The
searchandfetchtools are provided for ChatGPT. - Other MCP clients (Cursor, Windsurf, Cline, etc.): add the same URL as a Streamable HTTP server.
Available tools
| Tool | Description |
|---|---|
database_overview | Database totals |
search, fetch | Search interface used by ChatGPT |
search_genes, get_gene | Find a gene and get its summary |
get_gene_mutations | Mutations recorded in a gene |
search_cell_lines, get_cell_line | Find a cell line and get its summary |
top_genes_in_cell_line | Most frequently mutated genes in a cell line |
list_tissues, list_cancer_types | Tissues and cancer types with counts |
get_mhc_binding | Cached MHC-I binding predictions for a peptide |
Example questions
- Search CAN-IMMUNE for BRAF and summarise its mutations.
- What are the top mutated genes in MDA-MB-231?
- How many mutations and peptides are in the database?
- Which cancer types have the most mutations?
- Show the cached MHC binding for peptide FLDGNQIVT with HLA-A*02:11.
Usage and limits
The connector cannot modify any data. Queries return at most 100 rows and have a time limit. Anonymous use is allowed at a lower rate. If you sign in with Google, academic email addresses (.edu, .edu.au, .ac.*) get the highest limit and other verified addresses a standard limit. Only your email address is read, to set the limit, and it is not stored.
Data come from COSMIC, DepMap/CCLE and published neoantigen studies. If you use CAN-IMMUNE in your work, please cite it.